ThePeptide.expert
Database

Peptide profiles.

Filter by category, search by name. Each profile is graded on a five-tier evidence scale.

34 profiles

BPC-157

Body Protection Compound-157

Cat 1 — 2026
injectableoral
Evidence

15-amino acid peptide derived from human gastric juice. Promotes tissue repair, gut healing, and angiogenesis. Among the most-researched repair peptides available.

TB-500

Thymosin Beta-4 fragment

Cat 1 — 2026
injectable
Evidence

Synthetic fragment of Thymosin Beta-4. Promotes systemic tissue repair through actin regulation and stem cell activation. Often stacked with BPC-157.

Sermorelin

GHRH(1-29) / Geref

FDA approved
injectable
Evidence

The original FDA-approved GHRH analogue. Stimulates natural GH production through your own pituitary gland. Most natural approach to growth hormone optimization available.

Tesamorelin

Egrifta / Stabilized GHRH / GHRH analogue

FDA approved
injectable
Evidence

The most clinically validated GHRH analogue available. FDA-approved for visceral fat reduction. Emerging data for cognitive protection in early Alzheimer's and MCI. Widely prescribed off-label for body composition and longevity.

Ipamorelin

Growth Hormone Secretagogue (selective)

Cat 1 — 2026
injectable
Evidence

The most selective GH secretagogue available. Stimulates strong growth hormone release with minimal cortisol or prolactin side effects. Considered the gold standard secretagogue.

GHK-Cu

Copper peptide / Glycyl-L-histidyl-L-lysine-Cu²⁺

Cat 1 — 2026
injectabletopical
Evidence

Naturally occurring copper-binding peptide found in human plasma. Declines significantly with age. Influences over 4,000 genes. Strongest evidence base for topical skin applications.

Thymosin Alpha-1

Tα1 / Thymalfasin / Zadaxin

Cat 1 — 2026
injectable
Evidence

28-amino acid immune-modulating peptide derived from the thymus gland. Approved in 70+ countries as Zadaxin. Among the most clinically validated peptides globally.

PT-141

Bremelanotide / Vyleesi

FDA approved
injectablenasal
Evidence

FDA-approved peptide for sexual dysfunction. Works through central nervous system desire circuits — not vascular mechanisms like PDE5 inhibitors. Effective for both men and women.

Semax

ACTH(4-7)PGP

Cat 2 — review
nasalinjectable
Evidence

Russian-developed neuropeptide approved in Russia for stroke and TBI. Increases BDNF and NGF. Intranasal administration crosses blood-brain barrier effectively. Under FDA review for US Category 1 status.

Epitalon

Epithalamin / Tetrapeptide AEDG

Cat 2 — review
injectablenasal
Evidence

Pineal gland-derived tetrapeptide studied for telomere lengthening via telomerase activation. 40+ years of Russian research by Dr. Vladimir Khavinson. Under FDA review for Category 1 status.

MOTS-c

Mitochondrial ORF of 12S rRNA type-c

Cat 1 — 2026
injectable
Evidence

Mitochondria-derived peptide discovered in 2015. Acts as an exercise mimetic by activating the same metabolic pathways triggered by physical activity. Levels naturally decline with age.

GLP-3

Triple-Action Metabolic Compound (RT formulation)

RUO only
injectable
Evidence

A triple-action metabolic research compound combining GLP-1, GLP-2, and GLP-3 receptor activity. Studied for metabolic regulation, gut health, and appetite modulation in preclinical models.

CJC-1295 / Ipamorelin Stack

CJC-Ipa / GH Stack / Secretagogue Combination

Cat 1 — 2026
injectable
Evidence

The most commonly prescribed GH secretagogue combination in US longevity medicine. CJC-1295 provides GHRH stimulation while Ipamorelin provides ghrelin receptor stimulation — two complementary pathways for natural GH optimization.

GLOW Blend

AminoClub GLOW / Cellular Peptide Blend

Cat 1 — 2026
injectable
Evidence

A proprietary AminoClub peptide blend formulated for skin rejuvenation, cellular repair, and anti-aging. Combines synergistic peptides targeting collagen synthesis, skin barrier function, and cellular regeneration.

KLOW Blend

AminoClub KLOW / Cellular Peptide Blend

Cat 1 — 2026
injectable
Evidence

A proprietary AminoClub peptide blend formulated for metabolic optimization, body composition, and longevity. Targets the GH axis, metabolic pathways, and cellular health simultaneously.

Wolverine Stack

BPC-157 / TB-500 Combination / Recovery Stack

Cat 1 — 2026
injectable
Evidence

The most researched tissue repair combination in peptide science. BPC-157 and TB-500 work through complementary mechanisms — local repair signaling and systemic actin regulation — making them the gold standard recovery stack.

Ipamorelin

Growth Hormone Secretagogue (selective) / GHS

Cat 1 — 2026
injectable
Evidence

The most selective growth hormone secretagogue available. Stimulates strong GH release with minimal cortisol or prolactin side effects. Gold standard for GH axis optimization.

GHRP-2

Growth Hormone Releasing Peptide-2 / Pralmorelin

RUO only
injectable
Evidence

Potent GH secretagogue with stronger GH pulse than Ipamorelin but significant cortisol and prolactin elevation. Largely replaced by Ipamorelin in clinical settings.

GHRP-6

Growth Hormone Releasing Peptide-6

RUO only
injectable
Evidence

Early GH secretagogue notable for strong appetite stimulation via ghrelin pathway. Studied for cachexia and muscle wasting. Also has gastroprotective properties similar to BPC-157.

IGF-1 LR3

Insulin-like Growth Factor-1 Long R3

RUO only
injectable
Evidence

Modified IGF-1 with 3x longer half-life. Directly stimulates muscle protein synthesis and satellite cell activation independent of the GH axis. Significant cancer risk concern.

Follistatin-344

FST-344 / Myostatin Inhibitor

RUO only
injectable
Evidence

Myostatin inhibitor studied for exceptional muscle growth by blocking the body's natural muscle-growth limiter. Dramatic animal model results. Significant organ growth safety concerns.

Melanotan II

MT-II / α-MSH analogue

RUO only
injectable
Evidence

Non-selective α-MSH analogue studied for tanning sexual function and appetite suppression. Parent compound of FDA-approved PT-141. Non-selectivity creates more side effects.

AOD-9604

Anti-Obesity Drug 9604 / hGH fragment 177-191

Cat 1 — 2026
injectableoral
Evidence

Fat-burning fragment of human growth hormone. Stimulates lipolysis without the anabolic or glucose effects of full GH. Completed Phase IIb human trials. Program paused vs GLP-1 competition.

KPV

Lys-Pro-Val tripeptide / α-MSH fragment

Cat 1 — 2026
injectableoral
Evidence

Tripeptide fragment of alpha-MSH with potent gut anti-inflammatory effects. One of the few peptides with genuine oral bioavailability making it uniquely valuable for gut-specific research.

Dihexa

PNB-0408 / N-hexanoic-Tyr-Ile-(6) aminohexanoic amide

RUO only
injectableoral
Evidence

Estimated 7 million times more potent than BDNF at forming new synaptic connections in animal models. Developed at Washington State University for dementia research. Significant cancer concern via MET oncogene.

SS-31

Elamipretide / MTP-131 / Bendavia

RUO only
injectable
Evidence

Mitochondria-targeted tetrapeptide that protects the inner mitochondrial membrane. Reduces oxidative stress and restores ATP production. In Phase II and III clinical trials for heart failure and Barth syndrome.

DSIP

Delta Sleep-Inducing Peptide

RUO only
injectable
Evidence

Nonapeptide originally isolated from rabbit brain during slow-wave sleep in 1977. Promotes delta slow-wave sleep — the most restorative sleep phase. Studied for circadian rhythm regulation.

VIP

Vasoactive Intestinal Peptide

RUO only
nasalinjectable
Evidence

28-amino acid neuropeptide with remarkable anti-inflammatory lung-protective and cognitive properties. Significant research interest for Long COVID and chronic inflammatory response syndrome.

Gonadorelin

GnRH / Luteinizing Hormone-Releasing Hormone / Lutrepulse

FDA approved
injectable
Evidence

FDA-approved GnRH analogue. Maintains testicular function and fertility during testosterone replacement therapy. Standard component of TRT protocols to prevent testicular atrophy.

Kisspeptin-10

KP-10 / Metastin fragment

RUO only
injectable
Evidence

Hypothalamic peptide that drives GnRH pulsatility — the most upstream signal in the entire reproductive hormone cascade. Studied for libido fertility and hypogonadism research.

LL-37

Cathelicidin / hCAP-18 fragment

RUO only
injectabletopical
Evidence

Human host defense peptide with broad-spectrum antimicrobial and wound-healing properties. Naturally produced by immune cells. Dual antimicrobial plus healing mechanism is unique.

Argireline

Acetyl Hexapeptide-3 / Acetyl Hexapeptide-8

Cat 1 — 2026
topical
Evidence

Topical SNARE-inhibiting peptide that reduces facial expression lines by decreasing muscle contraction intensity. Often called a Botox alternative. Multiple human RCTs with wrinkle reduction data.

Matrixyl

Palmitoyl Pentapeptide-4 / Pal-KTTKS / Matrixyl 3000

Cat 1 — 2026
topical
Evidence

Signal peptide that mimics collagen breakdown fragments to stimulate fibroblasts to produce collagen elastin and fibronectin. One of the most evidence-backed topical cosmetic peptides with replicated human RCT data.

SNAP-8

Acetyl Octapeptide-3 / Extended Argireline

Cat 1 — 2026
topical
Evidence

Extended Argireline analogue with two additional amino acids for potentially greater SNARE inhibition at lower concentration. Often combined with Argireline for additive expression line reduction.